An Australian-American, Fran O’Neill, was born in Wangaratta, Australia, and currently lives and works between Australia and Brooklyn, New York.

O'Neill attended Monash University, Melbourne, Australia, earning a BFA and Post Graduate Degree. Her post-graduate work continued at the New York Studio School's Certificate Program, and her MFA was completed at Brooklyn College. She has received a Joan Mitchell Foundation award. O’Neill’s solo exhibitions include at: Sears Peyton Gallery, NYC; Hathaway Contemporary, Atlanta, GA; West End Gallery, Melbourne, Australia; David Schweitzer Contemporary, Bushwick, NY; Miller Gallery, Cincinnati, OH; BMG Gallery, Adelaide, Australia; TW Fine Art, Brisbane, Australia; Life on Mars Gallery, Brooklyn, NY, John Davis Gallery, NY; New York Studio School, NY; and Sussex College, Hastings, UK. In 2016 her work was exhibited at MOCA in Jacksonville, FL in a group exhibition titled Confronting the Canvas: Women of Abstraction, and most recently her work was included in Vital Presence, curated by David Cohen at 1GAPGallery, in Brooklyn and in November 2022; "Left Turn" at Equity Gallery, NYCO’Neill’s work has been included in various group shows throughout the USA and in Australia. She has recently taught at the New York Studio School, Arts Students League and Pratt Institute.

Her work resides in private collections in the USA, Australia and UK, and in the permanent collection of MOCA Jacksonville, FL.